Archive forSIBO

PROBIOTICS – To Take or Not to Take?

Is it good bacteria? Better check exactly what’s in the bottle

Professor Gregor Reid at the University of Western Ontario. A growing number of people have turned probiotics for a host of health reasons, including candida, digestion, brain development, diarrhea and boosting the immune system.

Professor Gregor Reid at the University of Western Ontario. A growing number of people have turned probiotics for a host of health reasons, including candida, digestion, brain development, diarrhea and boosting the immune system. THE CANADIAN PRESS/Dave Chidley

The organisms may help with many conditions, but vague labeling clouds benefits

Kathleen Goldhar tried for years to figure out what was causing her young daughter to suffer from persistent, sometimes agonizing stomach pains.

Since age three, the now seven-year-old girl had complained of intense cramps that would stick around for a couple of nights, subside and then return days or weeks later, usually when she ate.

With little insight from doctors, at least one trip to the hospital with cramps that caused the little girl to writhe in pain, and myriad tests producing no answers, the single mom took the advice of a nutritional consultant who recommended probiotics.

Ms. Goldhar began adding a powdered supplement to her daughter’s juice and within a couple of weeks noticed that her complaints diminished as the pain appeared to lessen.

“They seem to work,” she said from Toronto. “It does seem to be a digestion issue and she seems to be able to sort of handle her food better. Her stomach doesn’t hurt as much.”

Ms. Goldhar is one of a growing number of people who have turned to the bacterial critters for a host of health reasons, including candida, digestion, diarrhea, boosting brain development and boosting the immune system.

Probiotics are live organisms, usually helpful bacteria similar to those found in the human gut, that can change or restore the intestinal flora. They are present in such foods as sauerkraut, miso and fermented products, but can also be taken in pill or powder form.

There are billions of bacteria in the body – on skin, in the mouth, the intestines and other body parts – that can maintain general health by raising resistance to harmful bacteria.

The World Health Organization defines probiotics as “live micro-organisms which when administered in adequate amounts confer a health benefit on the host.”

The surge in popularity comes after manufacturers homed in on the category’s potential benefits and began adding them to everything from yogurt, infant formula and juices to bread, chewing gum and chocolate. They can even be found in some floor cleaners and aftershaves.

Marketers have claimed the naturally occurring bacteria can shorten the duration of colds, prevent diarrhea, overcome allergies and even reduce the risk of certain cancers.

But health experts say the hoopla over probiotics has overshadowed actual scientific proof that they improve health, leading to confusion for consumers deluged with claims about products containing the micro-organisms.

Gregor Reid, who specializes in the study of probiotics, was on the panel that created the WHO’s definition of probiotics and says many of the products claiming to contain them actually don’t – because the specific bacteria haven’t been proven in a human study to confer a health benefit.

“The majority of products on the market are not in fact probiotics,” said Dr. Reid, a University of Western Ontario professor and head of the Canadian Research and Development Centre for Probiotics at the Lawson Health Research Institute in London, Ont.

“When you call something a probiotic, there should be an expectation that it’s been clinically tested and shown to have a benefit, and unfortunately many products don’t. So the first step is getting companies to do the studies.”

The problem is that there are many different strains of friendly bacteria that perform many different functions. Most have not been proven to be effective in clinical trials.

For consumers, it’s not clear on food labels how much and what type of bacteria a product contains, making it difficult to know if the probiotics are best suited for a particular health ailment.

Only some companies, like yogurt maker Dannon, list the specific bacteria that have been shown in trials to help with certain health issues, like regularity and digestion.

The company settled a $35-million lawsuit last year with customers dissatisfied over health claims it was making about yogurt products, leading to more explicit labelling.

Some experts say that shouldn’t scare off consumers from using probiotics for conditions where there is some agreement on benefits, such as helping with some types of diarrhea, bowel regularity, colds and irritable bowel syndrome.

John Bienenstock, a professor of pathology and molecular medicine at McMaster University in Hamilton, said people have to look carefully at a particular product and determine exactly what it is.

“They have to look through the literature carefully, recognizing there is this problem of a lack of consistency of information and lack of consistency of products,” said Dr. Bienenstock, who’s also director of the Brain Body Institute.

“From a consumer point of view, it’s very important that when you go out and see what’s on the shelf, you know what’s on the bottle and what it can do… There are health benefits and there is hype.”

Regulatory agencies are trying to rein in the multi-billion-dollar industry, which saw consumer spending on probiotic supplements triple in the United States between 1994 and 2003.

The International Probiotics Association is planning a labeling scheme that would include a minimum bacterial count and an identification of the bacterial strain.

There is also a move afoot in Europe to control the claims with regulation that demands companies produce the scientific evidence to support their labeling.

Health Canada has developed a probiotics monograph, which includes detailed information on acceptable health claims, associated doses, source materials and required risk information.

It has also developed a guidance document that spells out when health claims can be made about food. The department website states that food products containing probiotics may have to remove the word if they’re not accompanied by “specific, validated statements about the benefits or effects of the micro-organism.”

Researchers say people need to scrutinize prebiotics just as closely. The sugar-type molecules are non-digestible foods that make their way through the digestive system and help good bacteria flourish. They are mostly found in carbohydrate fibres and can be taken in supplements or foods.

Dr. Reid said consumers have to research probiotic products themselves, using online sites like PubMed (www.ncbi.nlm. nih.gov/pubmed) to see what studies have been done to prove a company’s claims.

He would like to see it made easier to know the strain of bacteria, its properties, what it does, how long it lasts if it’s in powder form and where it goes in the body. Otherwise, he worries that skepticism over probiotics’ actual benefits will sully ones that have been scientifically proven to work.

“There needs to be more clinical evidence or companies need to stop calling their products probiotics,” he said.

“It shouldn’t be a fad. I think the ones that are properly scientifically documented will be here to stay, but the other ones hopefully don’t spoil it for everyone else.”

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WRONG AGAIN!

My 3rd bout of SIBO in 6 months - does it ever end?

I finished my antibiotics 12 days ago and my tummy was wonderful and once again, I thought I had left it all behind me.   WRONG!

I woke up this morning and it felt like someone had socked me as hard as they could right smack in the middle of my tummy, plus nausea like morning sickness.   I knew it was back -so I took off for my GI  Dr AGAIN.  This time he is trying a different drug since the last drug made me almost as sick as the SIBO did.

I’m leaving on vacation for the holidays, and this was not what I had in mind when I planned on enjoying myself. 

Once again, plans are made, plans are changed, plans get messed up.

As my husband always says, whenever we make plans, we make 3 sets.

1)  Everything goes as planned

2)  Everything goes as planned WITHOUT me.

3)  Everything goes as planned WITHOUT either of us because

he feels the need to stick close by.

Life with PIDD is always a one day at a time adventure. 

Guess this means, if you find yourself with similar problems, feel free to ask me about them- I’ve already been there- done that.

Hope your holidays are wonderful, healthy and happy.

I will enjoy mine, and make the best of this.

At least I won’t have to worry about gaining any weight- that’s really looking on the bright side.

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Timing, Turkey, Turmoil and Tomorrow/ AKA SIBO returns

I posted a few months ago about my trials with small bacterial overgrowth.   It took about 4 months on antibiotics to resolve.   I felt great for quite a while and just assumed I had seen the last of it.

WRONG.    About 6 weeks ago, it returned and I started the antibiotics right away.   Last week-end, I was supposed to go to San Francisco, but the pain in my tummy was like someone sucker-punched me right smack in the middle of my abdomen.   To make matters worse, I had constant ‘morning sickness’, also known as nausea.   I was unable to sleep during the night because for whatever reason, it seems to hurt the very most while reclining.   Cancel San Francisco- schedule Dr appts instead.

I had the same test for SIBO that I had 6 weeks ago and it showed that my levels of bacteria had more than doubled while on the meds.

I had to change to a new antibiotic since I had built up a resistance to the drug of choice from my GI Dr.  Since the test and the fasting were done the day before THANKSGIVING, needless to say- when the big TURKEY day arrived, the last thing on my mind was food.

Great way to diet.  When you are in the midst of a case of SIBO, and then the drug treatment that cures it- there is a level of turmoil that hits the ole GI tract.   I had to abstain from anything that looked tasty, thus the self-inflicted diet. 

Today and many days, I live my life with the song playing in my head from Little Orphan Annie- TOMORROW, TOMORROW- it’s ONLY A DAY AWAY.   Because I always assume tomorrow will be a much better day - and guess what - it usually is.

Why am I telling you this?  Because when it hits you, and at sometime it probably will (remember the description on the IDF web-site that says CVID causes BOTH upper respiratory and GI infections)? I want you to be prepared.   I believe many of us are so focused on preventing the upper respiratory infections, that we dismiss, or forget about other problems we may experience.   If you have a tummy ache that won’t let up- go get it checked out.   You might want to read my posts ‘Some notes I took at Duke’.

Feel free to post a comment and ask me anything you would like to regarding the symptoms and I will try to help.

 THE SUN WILL COME UP TOMORROW

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Full Disclosure regarding past posts

Remember the Headaches and What If’s post?   Followed by the information on SIBO, or bacterial overgrowth?  I got hit with the one, two punch.  I started antibiotics for the sinus infection and  re-activated my SIBO- the horrid tummy aches that keep me up at night.

I had to have another test for it last week, and sure enough- it’s flared up again.  I’m taking probiotics as well as the antibiotics for the tummy.

This seems to be a vicious cycle.  Have you experienced anything like this?   I’m beginning to think this might be fairly common for PIDD patients since I’ve heard of it so often of late.  It makes me not want to take an antibiotic whenever I get a sinus or upper respiratory infection because I know what will follow.   So, once again- should we, or shouldn’t we?  Back to the What If’s.

It seems that no matter how well we take care of ourselves,  just when we think we are on top of the world, BAM- we are off balance once again.   Such is life with PIDD.

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More about Probiotics and PIDD Patients

Just in case you did not read the comments from Dr. Bonilla of Children’s Hospital Boston and Harvard Medical School on my last post, please read  below.

His post will help us make informed decisions about whether or not we want to take probiotics.

“I must disagree with the comment of the GI doctor mentioned above. For most PID patients, one or a few parts of the immune system are impaired, but others work perfectly well. Normal gut bacteria are important for intestinal health, whether you have PID or not. Whenever the balance of bacteria is disturbed due to infection, medication, or other illness, probiotics can help restore the balance. Probiotic supplements aren’t necessary for everyone all the time, they will NOT “boost” immune function, but they can improve intestinal health, in general, for anyone, even someone with PID. They can’t hurt, try it, and see if you feel better”. Dr. F. A. Bonilla

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Probiotics and PIDD

There has been much discussion lately regarding the use of probiotics for PIDD patients.   The results seem to be different for our patient population than they are for the general population.  I do know that my GI doctor told me that a PIDD patient can’t differentiate between good and bad bacteria- so save your money.   But, my alternative health practitioner has also told me that whenever I take an antibiotic, I should take probiotics during and for a week afterward to neutralize the effects of the drugs.   So, I do.   I want to share some medical information that I’ve received regarding this discussion.

This first one is from an article on Medscape called

Probiotics and Prebiotics in Gastrointestinal Disorders

I have taken the following directly from the article

Effects on Systemic Immunity

Oral administration of probiotics has been shown to result in altered immunity at distant mucosal sites, including the female genital tract, the respiratory tract, the skin, and the nasal passages. Specific strains of Bifidobacterium and Lactobacillus appear to be promising in the treatment and/or prevention of eczema/dermatitis in infants and children.  It is interesting to note that in these studies, supplementation with the probiotic did not appear to alter bacterial numbers in the colon. This suggests that these results are owing to altered immunity rather than altered colonization.

Authors

Richard N. Fedorak, Karen L. Madsen

 

I also have another article to cite  - it is:

Pathophysiology and Medical/Nutritional Consequences of Small Intestinal Bacterial Overgrowth

By Janet Yang, MD and Mark Pimentel, MD, FRCP(C)

 Adjunctive Treatments

“Patients whose symptoms are refractory to conventional treatment may benefit from adjunctive treatments such as supplementation with non-pathogenic strains of bacteria to enhance endogenous protective mechanisms (probiotic therapy).   Probiotic bacteria, such as specific strains of lactobacilli and bifidobacteria, have been examined as possible methods for controlling or eliminating the growth of pathogenic bacterial, viral and fungal organisms.   Lactobacillus sp very greatly in their ability to protect the mucosa from injury produced by other organisms.  It is important to use only those species that have been documented efficacy in intestinal conditions, such as L rhamnosus and L plantarum 299V.

Their role in bacterial overgrowth is unproven”.

So, as you can see- the jury is still out on whether or not to take probiotics.  If you have had success with them, I would continue to use them at your own discretion.

If you are wondering if they are working -  I might save my money.

I will continue to monitor this topic since it is very important to PIDD patients.   I know I’ve personally struggled with the decision to take or not to take for several years nows.

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